Cross-browser reach
Selenium
Selenium's reach is the broadest in QA — real Safari on macOS, real Edge, every Chrome + Firefox version including Chromium derivatives, all driven by the W3C WebDriver protocol. For B2C apps with significant Safari traffic or regulated industries that require literal-browser sign-offs, this is decisive.
Cypress
Cypress added WebKit (Safari engine) in 10+ and Firefox earlier, but real Safari on macOS still requires Playwright or a cloud grid. For most B2B apps, Cypress's coverage is sufficient. For B2C apps with high Safari share, plan to pair Cypress with a Playwright smoke suite.